An antiviral meliacarpin from leaves of Melia azedarach L.

نویسندگان

  • Laura E Alché
  • Guillermo Assad Ferek
  • Milena Meo
  • Celia E Coto
  • Marta S Maier
چکیده

Bioassay guided purification of the ethyl acetate extract of leaves of Melia azedarach led to the isolation of the limonoid 1-cinnamoyl-3,11-dihydroxymeliacarpin, which showed IC50 values of 6 microM and 20 microM for vesicular stomatitis (VSV) and herpes simplex (HSV-1) viruses, respectively. Its structure was established by spectroscopic methods.

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عنوان ژورنال:
  • Zeitschrift fur Naturforschung. C, Journal of biosciences

دوره 58 3-4  شماره 

صفحات  -

تاریخ انتشار 2003